Zhi Zhong Wan

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治中丸 (Treat the Middle Pill)

Source: Simple Formulas for Health (1905)

Last updated October 1, 2026

Not yet clinically reviewed

Description

Zhi Zhong Wan (Treat the Middle Pill), from Simple Formulas for Health (1905).

Associated formula of Li Zhong Wan.

Indications: Sudden turmoil disorder with epigastric and abdominal pain, urge to vomit without vomiting, and urge to defecate without doing so.

Usage: For sudden turmoil disorder with pain and unproductive urges; one version substitutes Citri reticulatae Semen (ju he) for the tangerine peel.

Category: Formulas that Warm the Middle and Dispel Cold.

Source: Scheid V, Bensky D, Ellis A, Barolet R. Chinese Herbal Medicine: Formulas & Strategies, 2nd ed. Eastland Press, 2009, p. 261.

Composition

Herb Amount % Role Function
Ren Shen
as printed: Ginseng Radix (ren shen) 60g
60g 20% —
Gan Jiang
as printed: Zingiberis Rhizoma (gan jiang) 60g
60g 20% —
Bai Zhu
as printed: Atractylodis macrocephalae Rhizoma (bai zhu) 60g
60g 20% —
Gan Cao
as printed: Glycyrrhizae Radix preparata (zhi gan cao) 60g
60g 20% —
Chen Pi
as printed: Citri reticulatae Pericarpium (chen pi) 60g
60g 20% —

Energetics dose-weighted

The formula's overall nature, taste balance and channel reach, weighted by each herb's dose. Classical formulas often pair warm and cool herbs on purpose, so a net figure summarises the mix — it doesn't describe every herb in it.

Nature

Cold Cool Neutral Warm Hot

Net warm (+1.00)

From 100% of the weighed grams.

neutral warm hot

Grams by band: neutral 20%, warm 60%, hot 20%.

Taste

pungent sweet bitter
  • pungent 30%
  • sweet 40%
  • bitter 30%

From 100% of the weighed grams.

Channels reached

  • Spleen 100%
  • Lung 80%
  • Stomach 60%
  • Heart 60%
  • Kidney 20%

Share of the grams entering each channel, from 100% of the weighed grams.

Dose-weighted from each herb's recorded nature, taste and channels (missing values are left out, never counted as neutral). It describes the composition — it is not a recommendation.

Compare side by side with Liu Shen San →

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Formula family

Each entry reads as the larger formula written out: “+” adds its other catalogue cores, then the herbs none of them hold. A catalogue formula counts as a core only when at least 80% of its herbs are present, no more than 1 is absent, and the absent herb is not its chief.

Formula Network

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Similar Formulas by composition

Match score combines dosage-weighted composition (cosine, 70%) with shared-herb overlap (Jaccard, 30%).

Traditional formula information is for educational purposes only. Herbal formulas should be prescribed by a qualified practitioner — dosages and combinations are individualized and can interact with medications.

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