Qi Ju Di Huang Wan

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杞菊地黄丸 (Lycium Fruit, Chrysanthemum, and Rehmannia Pill)

Source: Yi Ji

Last updated October 1, 2026

Not yet clinically reviewed

retrobulbar neuritisretinitisoptic nerve atrophyvitreous opacityphotosensitivityphotophobiaredness, swelling and pain of eyesblurry visionexcessive tearing with exposure to windchronic glaucomageneral visual disturbancehypertensiondiabetes mellitushyperemiamenopause

Description

Qi Ju Di Huang Wan (Lycium Fruit, Chrysanthemum, and Rehmannia Pill), from the Yi Ji (Levels of Medicine).

Actions: Nourishes Liver and Kidney yin.

Presentation: Liver and Kidney yin deficiencies with eye disorders: blurred vision, dry eyes, tearing of the eyes with exposure to wind; dizziness, vertigo, tinnitus, and soreness of the lower back and knees.

Cautions:

  • Same as Liu Wei Di Huang Wan

Pharmacological effects reported:

  • Immunostimulant: mild; increased macrophage phagocytosis in mice
  • Hypoglycemic: 2.5 and 5.0 g/kg orally daily for 4 months lowered plasma glucose and water intake

Source: Chen JK, Chen TT. Chinese Herbal Formulas and Applications: Pharmacological Effects & Clinical Research. Art of Medicine Press, 2009, p. 640.

Composition

Herb Amount % Role Function
Shu Di Huang
as printed: Shu Di Huang (Radix Rehmanniae Praeparata) 240g [24g]
24g 25.81% Liu Wei base: tonifies Liver and Kidney yin
Shan Zhu Yu
as printed: Shan Zhu Yu (Fructus Corni) 120g [12g]
12g 12.9% Liu Wei base
Shan Yao
as printed: Shan Yao (Rhizoma Dioscoreae) 120g [12g]
12g 12.9% Liu Wei base
Ze Xie
as printed: Ze Xie (Rhizoma Alismatis) 90g [9g]
9g 9.68% Liu Wei base
Mu Dan Pi
as printed: Mu Dan Pi (Cortex Moutan) 90g [9g]
9g 9.68% Liu Wei base
Fu Ling
as printed: Fu Ling (Poria) 90g [9g]
9g 9.68% Liu Wei base
Gou Qi Zi
as printed: Gou Qi Zi (Fructus Lycii) 90g [9g]
9g 9.68% improves vision, treats eye disorders
Ju Hua
as printed: Ju Hua (Flos Chrysanthemi) 90g [9g]
9g 9.68% improves vision, treats eye disorders

Energetics dose-weighted

The formula's overall nature, taste balance and channel reach, weighted by each herb's dose. Classical formulas often pair warm and cool herbs on purpose, so a net figure summarises the mix — it doesn't describe every herb in it.

Nature

Cold Cool Neutral Warm Hot

Net neutral (0.00)

From 100% of the weighed grams.

cold cool neutral warm

Grams by band: cold 10%, cool 19%, neutral 32%, warm 39%.

Pairs warm and cool. 39% of the weighed grams are warm or hot and 29% cool or cold — the net is their average, not the whole story.

Small but decisive: Ze Xie 9g (cold, 10% of the grams). Dose weighting nearly cancels a herb this small, but it may be what the formula is for.

Taste

pungent sweet sour bitter bland
  • pungent 5%
  • sweet 63%
  • sour 13%
  • bitter 10%
  • bland 10%

From 100% of the weighed grams.

Channels reached

  • Kidney 90%
  • Liver 68%
  • Lung 42%
  • Spleen 23%
  • Heart 19%

Share of the grams entering each channel, from 100% of the weighed grams.

Dose-weighted from each herb's recorded nature, taste and channels (missing values are left out, never counted as neutral). It describes the composition — it is not a recommendation.

Compare side by side with Qing Pi Yin →

Preparation

Honey pills or decoction as for Liu Wei Di Huang Wan; for decoction use bracketed doses.

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Formula family

Each entry reads as the larger formula written out: “+” adds its other catalogue cores, then the herbs none of them hold. A catalogue formula counts as a core only when at least 80% of its herbs are present, no more than 1 is absent, and the absent herb is not its chief.

Formula Network

Formulas that share herbs with this one — the closer to the centre, the stronger the match. Click a node to explore.

Similar Formulas by composition

Match score combines dosage-weighted composition (cosine, 70%) with shared-herb overlap (Jaccard, 30%).

Traditional formula information is for educational purposes only. Herbal formulas should be prescribed by a qualified practitioner — dosages and combinations are individualized and can interact with medications.

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