Mai Wei Di Huang Wan

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麦味地黄丸 (Ophiopogonis, Schisandra, and Rehmannia Pill)

Source: Yi Ji

Last updated October 1, 2026

Not yet clinically reviewed

diabetes mellitusasthmatidal fevernight perspiration

Description

Mai Wei Di Huang Wan (Ophiopogonis, Schisandra, and Rehmannia Pill), from the Yi Ji (Levels of Medicine).

Actions: Nourishes Liver and Kidney yin; Astringes Lung qi and nourishes Lung yin.

Presentation: Kidney and Lung yin deficiencies: coughing, shortness of breath, tidal fever, night sweats, plus the yin-deficiency manifestations of Liu Wei Di Huang Wan.

Pharmacological effects reported:

  • Hypoglycemic: marked effect when glucose 180-350 mg/dL, little above 350 mg/dL; did not raise insulin and still worked in pancreatectomized dogs

Source: Chen JK, Chen TT. Chinese Herbal Formulas and Applications: Pharmacological Effects & Clinical Research. Art of Medicine Press, 2009, p. 642.

Composition

Herb Amount % Role Function
Shu Di Huang
as printed: Shu Di Huang (Radix Rehmanniae Praeparata) 240g [24g]
24g 26.67% Liu Wei base: tonifies Liver and Kidney yin
Shan Zhu Yu
as printed: Shan Zhu Yu (Fructus Corni) 120g [12g]
12g 13.33% Liu Wei base
Shan Yao
as printed: Shan Yao (Rhizoma Dioscoreae) 120g [12g]
12g 13.33% Liu Wei base
Ze Xie
as printed: Ze Xie (Rhizoma Alismatis) 90g [9g]
9g 10% Liu Wei base
Mu Dan Pi
as printed: Mu Dan Pi (Cortex Moutan) 90g [9g]
9g 10% Liu Wei base
Fu Ling
as printed: Fu Ling (Poria) 90g [9g]
9g 10% Liu Wei base
Mai Men Dong
as printed: Mai Dong (Radix Ophiopogonis) 90g [9g]
9g 10% tonifies Lung yin, stops cough and dyspnea
Wu Wei Zi
as printed: Wu Wei Zi (Fructus Schisandrae Chinensis) 60g [6g]
6g 6.67% tonifies and astringes Lung yin, stops cough

Energetics dose-weighted

The formula's overall nature, taste balance and channel reach, weighted by each herb's dose. Classical formulas often pair warm and cool herbs on purpose, so a net figure summarises the mix — it doesn't describe every herb in it.

Nature

Cold Cool Neutral Warm Hot

Net neutral (-0.03)

From 100% of the weighed grams.

cold cool neutral warm

Grams by band: cold 20%, cool 10%, neutral 23%, warm 47%.

Pairs warm and cool. 47% of the weighed grams are warm or hot and 30% cool or cold — the net is their average, not the whole story.

Taste

pungent sweet sour bitter bland
  • pungent 5%
  • sweet 58%
  • sour 17%
  • bitter 10%
  • bland 10%

From 100% of the weighed grams.

Channels reached

  • Kidney 90%
  • Liver 50%
  • Lung 40%
  • Heart 37%
  • Spleen 33%
  • Stomach 10%

Share of the grams entering each channel, from 100% of the weighed grams.

Dose-weighted from each herb's recorded nature, taste and channels (missing values are left out, never counted as neutral). It describes the composition — it is not a recommendation.

Compare side by side with Du Qi Wan →

Preparation

Honey pills or decoction as for Liu Wei Di Huang Wan; for decoction use bracketed doses.

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Formula family

Each entry reads as the larger formula written out: “+” adds its other catalogue cores, then the herbs none of them hold. A catalogue formula counts as a core only when at least 80% of its herbs are present, no more than 1 is absent, and the absent herb is not its chief.

Formula Network

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Similar Formulas by composition

Match score combines dosage-weighted composition (cosine, 70%) with shared-herb overlap (Jaccard, 30%).

Traditional formula information is for educational purposes only. Herbal formulas should be prescribed by a qualified practitioner — dosages and combinations are individualized and can interact with medications.

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