Si Sheng Wan

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四生丸 (Four-Fresh Pill)

Source: Fu Ren Liang Fang (1178)

Last updated October 1, 2026

Not yet clinically reviewed

nose bleedsvomiting of blood from heat in the blood

Description

Si Sheng Wan (Four-Fresh Pill), from the Fu Ren Liang Fang, is used to cool blood; stop bleeding.

Presentation: nose bleeds; vomiting of blood from heat in the blood.

Syndrome: Syndrome of bleeding.

Composition strategy:

  • fresh herbs cool blood and stop bleeding more strongly
  • fresh Ai Ye as gentle warm assistant prevents stasis without driving the blood
  • aromatic He Ye and Ai Ye disperse restrained Qi and heat

Source: Yang Y. Chinese Herbal Formulas: Treatment Principles and Composition Strategies. Churchill Livingstone Elsevier, 2010, p. 293.

Composition

Herb Amount % Role Function
Ce Bai Ye
as printed: Sheng Ce Bai Ye (raw Platycladi cacumen)
12g 26.67% Jun (Chief) fresh herb, cool blood, stop bleeding
Sheng Di Huang
as printed: Sheng Di Huang (Rehmanniae radix)
15g 33.33% Chen (Deputy) fresh herb, cool blood
He Ye
as printed: Sheng He Ye (raw Nelumbinis folium)
9g 20% Zuo (Assistant) fresh herb, cool blood, stop bleeding; aromatic disperses restrained Qi and heat
Ai Ye
as printed: Sheng Ai Ye (raw Artemisiae argyi folium)
9g 20% Zuo (Assistant) gently move and warm blood to prevent stasis from cold herbs

Energetics dose-weighted

The formula's overall nature, taste balance and channel reach, weighted by each herb's dose. Classical formulas often pair warm and cool herbs on purpose, so a net figure summarises the mix — it doesn't describe every herb in it.

Nature

Cold Cool Neutral Warm Hot

Net cool (-1.00)

From 100% of the weighed grams.

cold neutral warm

Grams by band: cold 60%, neutral 20%, warm 20%.

Taste

pungent sweet bitter
  • pungent 10%
  • sweet 17%
  • bitter 73%

From 100% of the weighed grams.

Channels reached

  • Liver 100%
  • Spleen 67%
  • Kidney 53%
  • Lung 47%
  • Heart 33%
  • Stomach 20%

Share of the grams entering each channel, from 100% of the weighed grams.

Dose-weighted from each herb's recorded nature, taste and channels (missing values are left out, never counted as neutral). It describes the composition — it is not a recommendation.

Compare side by side with Liu Shen San →

Preparation

Source: grind equal amounts into a paste and form pills. May be decocted, or the juice of the crushed raw herbs taken cool or warm, at the doses in parentheses.

Source: Scheid V, Bensky D, Ellis A, Barolet R. Chinese Herbal Medicine: Formulas & Strategies, 2nd ed. Eastland Press, 2009, p. 600.

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Match score combines dosage-weighted composition (cosine, 70%) with shared-herb overlap (Jaccard, 30%).

Traditional formula information is for educational purposes only. Herbal formulas should be prescribed by a qualified practitioner — dosages and combinations are individualized and can interact with medications.

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