Long Dan Xie Gan Tang

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龙胆泻肝汤 (Gentian Drain the Liver Decoction)

Source: Yi Fang Ji Jie (Collected Explanations of Medical Formulas) — Wang Ang (Qing, 1682)

Last updated July 22, 2026

Liver and Gallbladder excess fireUrogenital damp-heatAcute hepatitisHerpes zoster along Liver channelConjunctivitis from Liver fireMigraine from Liver Yang risingLeukorrhea from damp-heat

Description

Long Dan Xie Gan Tang (Gentian Drain the Liver Decoction) is the primary formula for draining excess fire and heat-damp from the Liver and Gallbladder channels. It is indicated for two distinct patterns: upward flaring of Liver fire causing head, ear, and eye symptoms; and downward flowing damp-heat along the Liver channel causing urogenital symptoms. The formula powerfully clears without injuring Yin.

Composition

Herb Amount % Role Function
Huang Qin 9g 13.04% Chen (Deputy) Clears heat from Liver and upper burner.
Ze Xie 12g 17.39% Zuo (Assistant) Drains dampness from Liver channel through urination.
Mu Tong 9g 13.04% Zuo (Assistant) Drains damp-heat through urination.
Che Qian Zi 9g 13.04% Zuo (Assistant) Clears heat, promotes urination, drains damp-heat.
Dang Gui 9g 13.04% Zuo (Assistant) Nourishes Blood to prevent bitter-cold herbs from injuring Yin.
Sheng Di Huang 9g 13.04% Zuo (Assistant) Cools Blood, nourishes Yin, prevents injury from draining herbs.
Chai Hu 6g 8.7% Shi (Envoy) Guides formula to Liver and Gallbladder channels.
Gan Cao 6g 8.7% Shi (Envoy) Harmonizes all herbs, protects Stomach.

Total weight: 72g

Preparation

Decoct in water 20–25 minutes. Take cool or at room temperature. Not for long-term use.

Dosage

Decoction: 1 dose/day. Pills: 6g twice daily. Short-term use only — discontinue when condition resolves.

Conditions Addressed

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Traditional formula information is for educational purposes only. Herbal formulas should be prescribed by a qualified practitioner — dosages and combinations are individualized and can interact with medications.

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