Huang Qi Jian Zhong Tang

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黄芪建中汤 (Astragalus Decoction to Construct the Middle)

Source: Jin Gui Yao Lue — Zhang Zhong-Jing (Eastern Han, c. 220)

Last updated October 1, 2026

Not yet clinically reviewed

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Description

Huang Qi Jian Zhong Tang (Astragalus Decoction to Construct the Middle), from the Jin Gui Yao Lue (Essentials from the Golden Cabinet) by Zhang Zhong-Jing.

Actions: Warms the middle jiao and tonifies qi; Harmonizes the interior and relieves pain.

Presentation: Deficiency and cold of the middle jiao with severe qi deficiency: abdominal pain that decreases with warmth and pressure, a sallow and dull complexion, and a pale tongue with a white coating; possibly palpitations, fidgeting, irritability, spontaneous perspiration, shortness of breath, lethargy, and a dry mouth and throat.

Composition: Xiao Jian Zhong Tang plus Huang Qi; the base formula tonifies and warms the middle, harmonizes the interior and relieves pain.

Toxicology: Acute toxicity: subcutaneous LD50 of the decoction in mice was 48 g/kg.

Pharmacological effects reported:

  • Gastrointestinal: suppressed gastric acid and promoted gastric-ulcer healing in rats
  • Immunostimulant: IgG rose (mean +1.59 mg/mL, p<0.05) after 20 doses in patients with GI disorders

Source: Chen JK, Chen TT. Chinese Herbal Formulas and Applications: Pharmacological Effects & Clinical Research. Art of Medicine Press, 2009, p. 475.

Composition

Herb Amount % Role Function
Yi Tang
as printed: Yi Tang (Maltosum) 1 cup [30g]
30g 35.71% —
Gui Zhi
as printed: Gui Zhi (Ramulus Cinnamomi) 9g
9g 10.71% —
Bai Shao
as printed: Bai Shao (Radix Paeoniae Alba, chao (dry-fried) with liquor) 18g
18g 21.43% —
Gan Cao
as printed: Zhi Gan Cao (Radix et Rhizoma Glycyrrhizae Praeparata cum Melle) 6g
6g 7.14% —
Sheng Jiang
as printed: Sheng Jiang (Rhizoma Zingiberis Recens, qie (sliced)) 9g
9g 10.71% —
Da Zao
as printed: Da Zao (Fructus Jujubae, bo (opened)) 12 pieces [4 pieces]
4pieces 100% —
Huang Qi
as printed: Huang Qi (Radix Astragali) 4.5g [12g]
12g 14.29% tonifies qi to treat qi deficiency

Energetics dose-weighted

The formula's overall nature, taste balance and channel reach, weighted by each herb's dose. Classical formulas often pair warm and cool herbs on purpose, so a net figure summarises the mix — it doesn't describe every herb in it.

Nature

Cold Cool Neutral Warm Hot

Net slightly warm (+0.50)

From 100% of the weighed grams.

cool neutral warm

Grams by band: cool 21%, neutral 7%, warm 71%.

Taste

pungent sweet sour bitter
  • pungent 16%
  • sweet 63%
  • sour 11%
  • bitter 11%

From 100% of the weighed grams.

Channels reached

  • Spleen 89%
  • Lung 79%
  • Stomach 54%
  • Liver 21%
  • Heart 18%

Share of the grams entering each channel, from 100% of the weighed grams.

1 herb without a dose in grams, so left out of every figure above: Da Zao.

Dose-weighted from each herb's recorded nature, taste and channels (missing values are left out, never counted as neutral). It describes the composition — it is not a recommendation.

Compare side by side with Li Zhong Wan →

Preparation

As Xiao Jian Zhong Tang: cook all but Yi Tang in 7 cups [1,400 mL] to 3 cups [600 mL], dissolve Yi Tang, take 1 cup [200 mL] warm three times daily; today use bracketed doses, cook twice, take in two doses.

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Formula family

Each entry reads as the larger formula written out: “+” adds its other catalogue cores, then the herbs none of them hold. A catalogue formula counts as a core only when at least 80% of its herbs are present, no more than 1 is absent, and the absent herb is not its chief.

Formula Network

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Similar Formulas by composition

Match score combines dosage-weighted composition (cosine, 70%) with shared-herb overlap (Jaccard, 30%).

Traditional formula information is for educational purposes only. Herbal formulas should be prescribed by a qualified practitioner — dosages and combinations are individualized and can interact with medications.

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