Gui Zhi Jia Fu Zi Tang

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桂枝加附子汤 (Cinnamon Twig Decoction Plus Aconite)

Source: Shang Han Lun — Zhang Zhong-Jing (Eastern Han, c. 220)

Last updated October 20, 2026

Not yet clinically reviewed

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Description

Gui Zhi Jia Fu Zi Tang (Cinnamon Twig Decoction Plus Aconite) is the formula given in Line 20 of the Shang Han Lun for a greater yáng disease in which promoted sweating gives way to incessant leaking sweat, with aversion to wind, difficult urination, and slightly tensed limbs that bend and stretch with difficulty.

Source: Mitchell C, Feng Y, Wiseman N. Shang Han Lun: On Cold Damage, Translation & Commentaries. Paradigm Publications, 1999, pp. 83–84.

Composition

Liquorice — estimated at the Chinese Pharmacopoeia's minimum content: about 469 mg of glycyrrhizic acid a day (zhi Gan Cao 46.88 g × 1.0 %). The EU Scientific Committee on Food considers 100 mg/day an upper limit for regular intake that protects most people. The estimate assumes all of it passes into what is taken, uses the pharmacopoeia's dry-weight minimum, and takes the amounts as one day's dose.

Sources

Sources: Chinese Pharmacopoeia 2020, 甘草 and 炙甘草, assay (glycyrrhizic acid not less than 1.8 % in the dispensed slices and 1.0 % in honey-fried liquorice, by dry weight). EU Scientific Committee on Food, Opinion on glycyrrhizinic acid and its ammonium salt, SCF/CS/ADD/EDUL/225 Final, 2003. The Committee notes this limit may not protect people with high blood pressure, electrolyte or fluid-balance disorders, slow gut transit, or reduced 11β-HSD2 activity.

Herb Amount % Role Function
Gui Zhi
as printed: 桂枝三两(去皮) (3 liang, remove bark); 46.875 g at 1 liang = 15.625 g (p. 64)
46.88g 25% —
Bai Shao
as printed: 芍药三两 (3 liang); 46.875 g at 1 liang = 15.625 g (p. 64); printed as 芍药 shao yao (peony, white or red not specified), linked to Bai Shao as in the catalogue's other Shang Han Lun rows
46.88g 25% —
Gan Cao
as printed: 甘草三两(炙) (3 liang, mix-fried); 46.875 g at 1 liang = 15.625 g (p. 64)
46.88g 25% —
Sheng Jiang
as printed: 生姜三两(切) (3 liang, cut); 46.875 g at 1 liang = 15.625 g (p. 64)
46.88g 25% —
Da Zao
as printed: 大枣十二枚(擘) (12 pieces, broken)
12pieces 92.31% —
Zhi Fu Zi
as printed: 附子一枚(炮,去皮,破八片) (1 piece, blast-fried, skin removed, broken into eight pieces); blast-fried (炮)
1pieces 7.69% —

Energetics dose-weighted

The formula's overall nature, taste balance and channel reach, weighted by each herb's dose. Classical formulas often pair warm and cool herbs on purpose, so a net figure summarises the mix — it doesn't describe every herb in it.

Nature

Cold Cool Neutral Warm Hot

Net neutral (+0.25)

From 100% of the weighed grams.

cool neutral warm

Grams by band: cool 25%, neutral 25%, warm 50%.

Pairs warm and cool. 50% of the weighed grams are warm or hot and 25% cool or cold — the net is their average, not the whole story.

Taste

pungent sweet sour bitter
  • pungent 38%
  • sweet 38%
  • sour 13%
  • bitter 13%

From 100% of the weighed grams.

Channels reached

  • Lung 75%
  • Spleen 75%
  • Stomach 50%
  • Heart 50%
  • Liver 25%

Share of the grams entering each channel, from 100% of the weighed grams.

2 herbs without a dose in grams, so left out of every figure above: Da Zao, Zhi Fu Zi.

Dose-weighted from each herb's recorded nature, taste and channels (missing values are left out, never counted as neutral). It describes the composition — it is not a recommendation.

Compare side by side with Gui Zhi Fu Zi Tang →

Preparation

(1) [For] the above six ingredients, use seven shēng of water. Boil to get three shēng, remove the dregs and take one shēng, warm. (2) [This is] Cinnamon Twig Decoction (guì zhī tāng) with the addition of aconite (fù zǐ). (3) One should rest [as described] in the method [for Cinnamon Twig Decoction (guì zhī tāng)]. (Mitchell, Feng & Wiseman 1999, p. 84, Line 20)

Conditions Addressed

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Formula family

Each entry reads as the larger formula written out: “+” adds its other catalogue cores, then the herbs none of them hold. A catalogue formula counts as a core only when at least 80% of its herbs are present, no more than 1 is absent, and the absent herb is not its chief.

Formula Network

Formulas that share herbs with this one — the closer to the centre, the stronger the match. Click a node to explore.

Similar Formulas by composition

Match score combines dosage-weighted composition (cosine, 70%) with shared-herb overlap (Jaccard, 30%).

Traditional formula information is for educational purposes only. Herbal formulas should be prescribed by a qualified practitioner — dosages and combinations are individualized and can interact with medications.

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