Ku Zhi San

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Source: Wai Ke Shi San Fang Kao

Last updated October 1, 2026

Not yet clinically reviewed

Description

Ku Zhi San (Hemorrhoid- Necrotizing Powder), from Investigations of Thirteen Formulas for External Medicine (Wai Ke Shi San Fang Kao).

Actions: Eliminate putridity and heal the wound, draw out toxin and necrotize hemorrhoids. Indicated for the treatment of hemorrhoids in various stages, with hemorrhoid upon the dentate line, bloody stool, or pain

Indications: Arsenicum Sublimatum ( pi shuang ) is poisonous, use this powder should be cautious. Dosage should be not too large, and long-term use is also inadvisable

Source: Xi S, Gong Y. Essentials of Chinese Materia Medica and Medical Formulas: New Century Traditional Chinese Medicine. Academic Press/Elsevier, 2017, pp. 861–873.

Composition

Herb Amount % Role Function
Pi Shuang
as printed: Arsenicum Sublimatum (pi shuang) 60 g
60g 43.48% —
Ming Fan
as printed: Alumen (bai fan) 60 g
60g 43.48% —
Peng Sha
as printed: Borax (peng sha) 6 g
6g 4.35% —
Liu Huang
as printed: Sulfur (liu huang) 6 g
6g 4.35% —
Xiong Huang
as printed: Realgar (xiong huang) 6 g
6g 4.35% —

Energetics dose-weighted

The formula's overall nature, taste balance and channel reach, weighted by each herb's dose. Classical formulas often pair warm and cool herbs on purpose, so a net figure summarises the mix — it doesn't describe every herb in it.

Nature

Cold Cool Neutral Warm Hot

Net cool (-0.83)

From 100% of the weighed grams.

cold cool neutral warm

Grams by band: cold 44%, cool 4%, neutral 44%, warm 9%.

Taste

pungent sweet sour bitter salty
  • pungent 24%
  • sweet 2%
  • sour 70%
  • bitter 2%
  • salty 2%

From 100% of the weighed grams.

Channels reached

  • Lung 91%
  • Liver 91%
  • Spleen 87%
  • Large intestine 52%
  • Stomach 9%
  • Kidney 4%

Share of the grams entering each channel, from 100% of the weighed grams.

Dose-weighted from each herb's recorded nature, taste and channels (missing values are left out, never counted as neutral). It describes the composition — it is not a recommendation.

Compare side by side with San Pin Yi Tiao Qiang →

Preparation

Grind the ingredients into fine powder, put it into sand container, seal up its mouth with paper, after calcining and cooling, keep it in a dry and cool place for about 2 months until fire toxin is eliminated, then grind into powder, and apply a little powder on the affected area

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Formula Network

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Similar Formulas by composition

Match score combines dosage-weighted composition (cosine, 70%) with shared-herb overlap (Jaccard, 30%).

Traditional formula information is for educational purposes only. Herbal formulas should be prescribed by a qualified practitioner — dosages and combinations are individualized and can interact with medications.

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