Pi Shuang

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Arsenolite / arsenic trioxide (As2O3)

Pinyin: Pi Shuang
Arsenic

☯ TCM Properties

Category: external applications
Temperature: neutral
Taste: pungent, sour
Meridians: spleen, lung, liver
Functions:

Eliminates phlegm and calms dyspnea; Prevents malaria; Kills parasites and erodes sores topically

Traditional Chinese Uses

Pi Shuang is refined arsenic trioxide (As2O3, "arsenic frost"), a highly toxic mineral substance prepared by sublimation of arsenical ores. Pungent and sour (classically noted as hot) and entering the Spleen, Lung and Liver channels, it was traditionally used in minute, carefully processed doses to transform cold Phlegm and calm wheezing in chronic asthma, to check malarial disorders, and to kill parasites. Topically it erodes rotten flesh and toxic sores, and was applied to obstinate ulcers, scrofula, tinea, hemorrhoids and abnormal granulation tissue.

This is a poison of the highest order: arsenic destroys cellular respiration, damages the liver and gastrointestinal tract, and is readily lethal. It is strictly contraindicated in pregnancy and in weak patients, must never be self-used, and its manufacture and sale are legally restricted. Historical and modern hospital-supervised use only.

Botanical Description

Pi Shuang is the Chinese name for refined arsenic trioxide (As2O3), historically prepared by sublimation of arsenical ores such as arsenolite or realgar (Pi Shi). It appears as a white, crystalline, odorless powder, extremely toxic in even minute oral doses, with a recorded fatal dose under 100 mg. Classical Chinese materia medica employed Pi Shuang externally for malignant ulcers and obstinate skin lesions, and internally in trace amounts within compound formulas for chronic asthma and certain malignancies. Modern pharmacology has confirmed activity of arsenic trioxide against acute promyelocytic leukemia, where it is administered as a tightly controlled pharmaceutical (Trisenox). Unregulated internal use is universally discouraged due to severe systemic toxicity, carcinogenicity, and risk of fatal poisoning.

Dosage

FormAmount Frequency Duration Population Notes
poultice As needed Daily

This information is for educational purposes only and is not intended to replace professional medical advice. Always consult a qualified healthcare provider before using any herbal remedy, especially if you are pregnant, nursing, or taking medications.

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