Huang Lian Tang

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黄连汤 (Coptis Decoction)

Source: Shang Han Lun — Zhang Zhong-Jing (Eastern Han, c. 220)

Last updated October 1, 2026

Not yet clinically reviewed

gastric ulcerduodenal ulceratrophic gastritisgastroenteritisacid regurgitationepigastric painstomatitisacute food poisoninghangover

Description

Huang Lian Tang (Coptis Decoction), from the Shang Han Lun (Discussion of Cold-Induced Disorders) by Zhang Zhong-Jing.

Actions: Regulates heat and cold imbalances; Harmonizes the Stomach and corrects the reversed flow of qi.

Presentation: Heat in the chest and cold in the Stomach: irritability, a stifling sensation in the chest, nausea, abdominal pain, borborygmus, diarrhea, a white, slippery tongue coating, and a wiry pulse.

Cautions:

  • Do not use for nausea, vomiting and stomach pain due to yin deficiency.

Toxicology: Very low toxicity: oral powder at 27 g/kg for 7 days (about 400x the therapeutic dose) caused no deaths or behavioral abnormalities in mice.

Pharmacological effects reported:

  • Antitumor: inhibited esophageal cancer cell lines in vitro; berberine from Huang Lian considered a main active constituent

Source: Chen JK, Chen TT. Chinese Herbal Formulas and Applications: Pharmacological Effects & Clinical Research. Art of Medicine Press, 2009, p. 271.

Composition

Herb Amount % Role Function
Huang Lian
as printed: Huang Lian (Rhizoma Coptidis) 9g [6g]
6g 16.67% Jun (Chief) clears heat in the Stomach and upper jiao
Gan Jiang
as printed: Gan Jiang (Rhizoma Zingiberis) 9g [6g]
6g 16.67% Chen (Deputy) warms the middle and lower jiaos
Gui Zhi
as printed: Gui Zhi (Ramulus Cinnamomi) 9g [6g]
6g 16.67% Chen (Deputy) helps Gan Jiang disperse cold; warms and opens the channels and collaterals
Ban Xia
as printed: Ban Xia (Rhizoma Pinelliae, xi (washed)) 0.5 cup [9g]
9g 25% Chen (Deputy) harmonizes the Stomach and relieves nausea
Ren Shen
as printed: Ren Shen (Radix et Rhizoma Ginseng) 6g [3g]
3g 8.33% Zuo (Assistant) tonifies and harmonizes the middle jiao
Da Zao
as printed: Da Zao (Fructus Jujubae, bo (opened)) 12 pieces [4 pieces]
4pieces 100% Zuo (Assistant) tonifies and harmonizes the middle jiao
Gan Cao
as printed: Zhi Gan Cao (Radix et Rhizoma Glycyrrhizae Praeparata cum Melle) 9g [6g]
6g 16.67% Zuo (Assistant) tonifies the middle jiao and harmonizes the herbs

Energetics dose-weighted

The formula's overall nature, taste balance and channel reach, weighted by each herb's dose. Classical formulas often pair warm and cool herbs on purpose, so a net figure summarises the mix — it doesn't describe every herb in it.

Nature

Cold Cool Neutral Warm Hot

Net slightly warm (+0.50)

From 100% of the weighed grams.

cold neutral warm hot

Grams by band: cold 17%, neutral 17%, warm 50%, hot 17%.

Taste

pungent sweet bitter
  • pungent 50%
  • sweet 29%
  • bitter 21%

From 100% of the weighed grams.

Channels reached

  • Lung 83%
  • Spleen 83%
  • Stomach 75%
  • Heart 75%
  • Large intestine 17%
  • Gallbladder 17%

Share of the grams entering each channel, from 100% of the weighed grams.

1 herb without a dose in grams, so left out of every figure above: Da Zao.

Dose-weighted from each herb's recorded nature, taste and channels (missing values are left out, never counted as neutral). It describes the composition — it is not a recommendation.

Compare side by side with Liu Shen San →

Preparation

Source: cook in 10 cups [2,000 mL] water to 6 cups [1,200 mL]; take 1 cup [200 mL] warm, strained, three times during the day and twice at night. Today decocted at the bracketed doses.

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Formula family

Each entry reads as the larger formula written out: “+” adds its other catalogue cores, then the herbs none of them hold. A catalogue formula counts as a core only when at least 80% of its herbs are present, no more than 1 is absent, and the absent herb is not its chief.

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Match score combines dosage-weighted composition (cosine, 70%) with shared-herb overlap (Jaccard, 30%).

Traditional formula information is for educational purposes only. Herbal formulas should be prescribed by a qualified practitioner — dosages and combinations are individualized and can interact with medications.

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