Yang Jin Hua

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Datura metel L.

Not yet clinically reviewed

Family: Solanaceae Pinyin: Yang Jin Hua
Hindu Datura Flower

Traditionally used for

  • Eye health
  • Cough & breathing
  • Digestion
  • Sleep
  • Nerves & recovery
  • Pain & joints
  • Skin

Cautions & contraindications

  • Pregnancy
  • Heart conditions
  • Toxic — professional use only
Strong evidence · 1 study

☯ TCM Properties

Category: transforming phlegm
Temperature: warm
Taste: pungent
Meridians: lung, liver
Functions:

Dispels Wind-Damp, relieves cough and dyspnea, relieves spasms and stops pain

Traditional Chinese Uses

Yang Jin Hua is the dried flower of Datura metel (Solanaceae), a pungent, warm, highly toxic herb entering the Lung and Liver channels. Traditionally it warms and quiets the Lung to relieve cough and wheezing in chronic asthma and cough without phlegm-heat, and it stops pain and spasm—used for epigastric and rheumatic pain and, in classical surgery, as an anesthetic. It also settles Wind and convulsions. Because its actives are the anticholinergic tropane alkaloids scopolamine, hyoscyamine, and atropine, the therapeutic dose is minute (roughly 0.3-0.6 g decocted, or 0.1-0.2 g in pills and powders). Overdose causes dry mouth, hot flushed skin, dilated pupils, blurred vision, rapid heartbeat, agitation, and delirium. It is contraindicated in pregnancy, glaucoma, hypertension, tachycardia, and in weak or feverish patients, and is dangerously confused with non-toxic Ling Xiao Hua (Campsis). Use only under strict medical supervision.

Western Herbalism Properties

Actions:
antispasmodicanalgesicsedative

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Botanical Description

Yang Jin Hua is the dried flower of Datura metel L. (Solanaceae), the downy thorn-apple or hindu datura, an erect annual or short-lived perennial herb 0.5 to 1.5 m tall with stout branching stems and broadly ovate, sinuate to entire leaves. The large solitary upward-facing trumpet-shaped flowers are 14 to 20 cm long, white to pale purple or yellow, single or double; the prickly globose capsule splits irregularly to release numerous flattened brown seeds. WARNING: All parts contain the tropane alkaloids hyoscyamine, scopolamine, and atropine and are highly toxic, producing anticholinergic delirium, mydriasis, tachycardia, hyperthermia, and in overdose death; the herb is a restricted drug in China and many countries. In traditional Chinese medicine the flower is acrid, warm, and toxic, entering the Lung and Liver channels; it stops cough and asthma, relieves pain, and calms convulsions, and was historically used as a surgical anesthetic.

Dosage

Form Amount Frequency Duration Population Notes
powder 0.3–0.6 g — — — ChP 2025. 宜入丸散 — preferably in pills or powder. May also be smoked in divided doses, total not exceeding 1.5 g/day. Contraindicated in pregnancy, in exterior invasion, in phlegm-heat cough and wheezing, and in glaucoma, hypertension and tachycardia. Corrected from a generic 6-15g decoction filler value generated from tcm_category.
topical Appropriate amount — — — ChP 2025. 外用适量。

Evidence Tier

Strong evidence · 1 study

Recorded studies by study design, strongest design at the top. This is a study-design tier only, not a GRADE rating: it does not weigh risk of bias, consistency or precision.

Systematic review / meta-analysis

1

1 verified · 0 unverified

Show the study

Randomized controlled trial

0

Other clinical trial

0

Observational / case report

0

In vitro / animal

0

Other / unclassified

0

Verified: design read from PubMed for a DOI that resolves to the cited paper Unverified: taken from the study's recorded description

Clinical Studies

Efficacy of extracts from Datura Metel L. for Psoriasis: a meta-analysis of case series and single-arm studies

Sang Xiaopu; Bi Huanzhou; Si Xinlei; Wang Yihang; Shi Xianjie; Wu Fenfang (2023) BMC Complementary Medicine and Therapies systematic review Verified: Systematic review / meta-analysis

Meta-analysis of nine studies totalling 1778 psoriasis patients treated with Datura metel extract preparations in China. Pooled cure rate was 0.48 (95% CI 0.33-0.62) for intravenous therapy and 0.42 (95% CI 0.17-0.68) for oral therapy; pooled effective rate was 0.91 (95% CI 0.84-0.97) intravenously and 0.94 (95% CI 0.88-0.99) orally. The authors stress that every included study was a case series or single-arm study with no control group, and that selection and publication bias very likely inflate these figures. The finding is included because it documents a use of this drug, systemic administration for psoriasis, that is separate from its analgesic, antitussive and anaesthetic indications and from the anticholinergic poisoning literature; it is not evidence of efficacy at the standard of a controlled trial. Systemic dosing of a Datura preparation carries the full tropane alkaloid risk described in the corresponding Datura metel record.

⚠ Safety & Contraindications

  • Pregnancy
  • Heart conditions
  • Toxic — professional use only

Contraindications

Contraindicated in pregnancy, in glaucoma, in prostatic enlargement or urinary retention, in tachyarrhythmia, and in the elderly or debilitated.

Safety Warnings

  • Narrow therapeutic margin; doses are small and precisely specified.
  • Additive with other anticholinergic drugs — tricyclic antidepressants, antihistamines, antiparkinsonian agents.
  • Impairs vision and alertness; patients must not drive.

⚠ Toxicity Information

Level: toxic
Toxic compounds: Tropane alkaloids — scopolamine (hyoscine), hyoscyamine, atropine.
Symptoms:

Dry mouth, dilated pupils and blurred vision, flushing, urinary retention, tachycardia, then delirium, hallucination, hyperthermia and coma — the classical anticholinergic syndrome.

Historical Texts

Ben Cao Gang Mu (Compendium of Materia Medica), Li Shizhen

Ming dynasty, 1596
Entered under Man Tuo Luo Hua, the flower, which is the plant part that constitutes Yang Jin Hua. Li Shizhen records the flower taken with hot wine to produce insensibility sufficient for cautery and minor surgery, and describes testing the intoxicating and laughter-inducing effect himself. This is the classical basis for the Chinese anaesthetic use of the drug and it concerns the flower specifically, whereas the general Datura metel record in this database covers the whole plant.

This information is for educational purposes only and is not intended to replace professional medical advice. Always consult a qualified healthcare provider before using any herbal remedy, especially if you are pregnant, nursing, or taking medications.

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