Water-pear

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Syzygium guineense

Family: Myrtaceae Genus: Syzygium Species: guineense

Synonyms: Calyptranthes guineensis, Eugenia guineensis, Syzygium fourcadei, Eugenia fourcadei

Water-pear
Water-pear

Western Herbalism Properties

Actions:
astringentantimicrobialanti-inflammatory

Botanical Description

Syzygium guineense, the water-pear or waterberry, is a medium to large evergreen or semi-deciduous tree in the myrtle family (Myrtaceae), broadly distributed across tropical Africa from Senegal and Ethiopia south to South Africa and Madagascar, where it occupies riverine forest, woodland, and montane forest from sea level to over 2400 meters. The species is taxonomically variable and several subspecies (subsp. guineense, subsp. afromontanum, subsp. macrocarpum, subsp. barotsense) are recognised. Mature trees commonly reach 15-30 meters with a straight bole bearing rough, longitudinally fissured, pale grey to brown bark and a dense, dark-green, often spreading crown. Leaves are opposite, simple, elliptic to oblanceolate, 6-18 cm long, leathery, glabrous, with a fine intramarginal vein and many translucent gland dots visible against light. Inflorescences are terminal or subterminal corymbose panicles bearing many creamy-white fragrant flowers with four small petals and a showy mass of long white stamens up to 1 cm long. Fruits are ellipsoid to globose fleshy berries 1-2 cm across, ripening dark purple to almost black, edible and sweetish-astringent.

Native Region: Angola, Benin, Botswana, Burkina, Burundi, Cabinda, Cameroon, Central African Repu, Chad, Congo, Eritrea, Ethiopia, Gabon, Gambia, Ghana, Guinea, Guinea-Bissau, Ivory Coast, Kenya, KwaZulu-Natal, Liberia, Malawi, Mali, Mozambique, Namibia, Nigeria, Northern Provinces, Rwanda, Saudi Arabia, Senegal, Sierra Leone, Somalia, Sudan, Swaziland, Tanzania, Togo, Uganda, Yemen, Zambia, Zaïre, Zimbabwe

Active Constituents

Hydrolysable and condensed tannins (including gallotannins/ellagitannins)

Tannins / polyphenols

Concentration: Abundant in bark and leaves

Astringent polyphenols that underpin the traditional use of bark and leaf decoctions for diarrhoea and wounds and contribute to antioxidant and antimicrobial activity.

Flavonoids (quercetin, myricetin and their glycosides)

Flavonoids

Concentration: Present in leaves and fruit

Contribute antioxidant, anti-inflammatory and alpha-glucosidase-inhibitory activity reported for leaf extracts.

Triterpenoids (e.g. betulinic, oleanolic and ursolic acid types)

Pentacyclic triterpenoids

Concentration: Isolated from bark and root extracts

Associated with anti-inflammatory, antimicrobial and cytoprotective effects observed in experimental studies of the species.

Phenolic acids (gallic and ellagic acid)

Phenolic acids

Concentration: Present across leaf, bark and fruit

Antioxidant and antimicrobial phenolics that add to the radical-scavenging capacity of extracts.

Sterols and essential-oil components

Phytosterols and volatile terpenes

Concentration: Minor constituents of leaves and bark

Reported among the isolated constituents; contribute to the overall pharmacological profile though individually less characterised.

Preparation Methods

Bark decoction

Parts: bark

Pieces of bark are boiled in water and the strained astringent liquid taken in small amounts, traditionally across sub-Saharan Africa for diarrhoea, dysentery and stomach complaints. Tannin content makes strong or prolonged use potentially irritating.

Leaf decoction / infusion

Parts: leaves

Fresh or dried leaves are simmered in water and the liquid used internally for fevers, malaria and blood-sugar complaints or externally to wash wounds; this preparation is the one most studied in antidiabetic and antimalarial animal models.

Root preparation

Parts: roots

Root pieces are decocted in traditional practice for pain, gastrointestinal and infectious conditions; roots and bark should be used cautiously given their high tannin and saponin content.

Edible fruit

Parts: fruit

The ripe purple-black berries are eaten fresh as a food and mild astringent, and are a source of anthocyanins and vitamin C.

Clinical Studies

Antimalarial activity of Syzygium guineense during early and established Plasmodium infection in rodent models

Tadesse SA, Wubneh ZB (2017) BMC Complementary and Alternative Medicine Preclinical (in vivo, mouse malaria model)

Crude leaf extract of S. guineense produced significant, dose-dependent suppression of Plasmodium berghei parasitaemia in both suppressive and curative rodent models, supporting the plant's ethnomedicinal use against malaria.

Acute and Subacute Toxicity of Methanol Extract of Syzygium guineense Leaves on the Histology of the Liver and Kidney and Biochemical Compositions of Blood in Rats

Loha M, Mulu A, Abay SM, Ergete W, Geleta B (2019) Evidence-Based Complementary and Alternative Medicine Preclinical (in vivo toxicology, rat)

Methanol leaf extract showed no acute lethality up to 2000 mg/kg and no significant adverse histological or biochemical changes over repeated dosing, indicating a wide margin of safety for the traditionally used leaf preparation.

Historical Texts

Traditional sub-Saharan African ethnomedicine (oral tradition, documented in later ethnobotanical surveys)

Pre-modern to present
Across West, East and Southern Africa the bark, leaves, roots and fruit of the waterberry have long been used for diarrhoea and dysentery, fevers and malaria, wounds, pain and stomach ailments; these uses were transmitted orally rather than in a classical written text.

References

  1. Tadesse SA, Wubneh ZB. Antimalarial activity of Syzygium guineense during early and established Plasmodium infection in rodent models . BMC Complementary and Alternative Medicine (2017) [DOI]
  2. Loha M, Mulu A, Abay SM, Ergete W, Geleta B. Acute and Subacute Toxicity of Methanol Extract of Syzygium guineense Leaves on the Histology of the Liver and Kidney and Biochemical Compositions of Blood in Rats . Evidence-Based Complementary and Alternative Medicine (2019) [DOI]

This information is for educational purposes only and is not intended to replace professional medical advice. Always consult a qualified healthcare provider before using any herbal remedy, especially if you are pregnant, nursing, or taking medications.

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