Quan Shen

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Polygonum bistorta L. (syn. Bistorta officinalis Delarbre)

Genus: Polygonum Species: bistorta Pinyin: Quan Shen
Bistort rhizome拳参

☯ TCM Properties

Category: clearing heat
Temperature: cool
Taste: bitter
Meridians: lung, liver, large intestine
Functions:

Clears Heat and Resolves Toxicity; Cools the Blood and Stops Bleeding; Disperses Swelling and Dissipates Nodules; Calms the Spirit and Settles Fright; Astringes the Intestines and Stops Diarrhea

Traditional Chinese Uses

Quan Shen (bistort rhizome, snakeweed) is a cool, bitter herb used in Chinese medicine to clear Heat toxin and stop bleeding. It treats carbuncles, boils, and skin infections from Heat toxin accumulation, and its hemostatic action addresses bleeding conditions from Heat in the Blood — including hematemesis, uterine bleeding, and hematochezia. Its secondary use for Wind-type convulsions and tremors reflects its calming action on internally generated Heat-Wind.

Western Herbalism Properties

Actions:
astringent

Botanical Description

Polygonum bistorta (syn. Bistorta officinalis), commonly known as bistort or snakeweed, is a perennial herb of the family Polygonaceae found across temperate Eurasia in damp meadows, streamsides, and montane grasslands. It grows 30 to 80 cm tall from a thick, twice-bent (S-shaped) rhizome that is dark brown externally and pinkish within. Basal leaves are long-stalked, oblong to ovate-lanceolate with a truncate or somewhat decurrent base, while stem leaves are smaller and clasping. From early to midsummer, dense cylindrical terminal spikes of small pink to pale rose flowers are borne on erect, unbranched stems. The rhizome is exceptionally rich in tannins, which underlie its long-recognized astringent properties in both Chinese and European herbal traditions.

Active Constituents

Condensed tannins (flavan-3-ol / procyanidin derivatives)

Polyphenol (tannin)

Concentration: High; total tannins roughly 15-20% of rhizome weight

The dominant constituent class, responsible for the astringent, antidiarrheal, hemostatic and topical anti-inflammatory actions of the rhizome.

Gallic acid and galloyl derivatives

Phenolic acid

Concentration: Prominent among the phenolics

Antioxidant and antibacterial phenolic; a major component of the aqueous extract and a marker of the tannin-related phenolic fraction.

Chlorogenic acid

Hydroxycinnamic acid ester

Concentration: One of the main phenolics of the aqueous extract

Antioxidant and anti-inflammatory phenolic acid contributing to the extract's activity in in-vitro and animal models.

Catechins and procyanidins

Flavan-3-ol / proanthocyanidin

Concentration: Significant

Flavan-3-ol monomers and oligomers that provide antioxidant and antibacterial activity and underpin the astringent properties.

Bistortaside A

Tannin-related glucoside (3-methyl-gallic acid glucopyranoside)

Concentration: Isolated as a characteristic compound

A rhizome-specific tannin-related compound identified during phytochemical study, illustrating the galloyl-glucoside chemistry of the plant.

Quercetin-3'-O-beta-D-glucopyranoside

Flavonol glycoside

Concentration: Minor

An antioxidant flavonol glycoside co-isolated with the tannin fraction.

Oxalic acid and organic acids

Organic acid

Concentration: Present

Contribute to the sour/astringent character; high oxalate content is one reason prolonged internal use is limited.

⚠ Drug Interactions

Oral iron supplements and alkaloidal/mineral drugs

Minor Evidence: Probable

The very high tannin content of the rhizome can bind iron, alkaloids and some other orally administered drugs in the gut, forming insoluble complexes that reduce their absorption.

Clinical note: Separate ingestion of tannin-rich Quan Shen preparations from oral iron and alkaloid-based medications by at least 2 hours.

Dosage

FormAmount Frequency Duration Population Notes
decoction 6-15g Daily

Preparation Methods

Decoction (water extraction)

Parts: Dried rhizome

Roughly 4.5-9 g of dried rhizome decocted in water and taken orally to clear heat, resolve toxicity and cool the blood. Because of the high tannin/oxalate content, internal use is generally short-term.

Topical wash / gargle

Parts: Dried rhizome

A stronger decoction used externally as a wash or gargle for sores, mouth ulcers, sore throat and bleeding, exploiting the astringent, antibacterial tannin fraction.

Clinical Studies

Antibacterial and anti-inflammatory activity of bistort (Bistorta officinalis) aqueous extract and its major components. Justification of the usage of the medicinal plant material as a traditional topical agent

Pawłowska KA, Hałasa R, Dudek MK, Majdan M, Jankowska K, Granica S (2020) Journal of Ethnopharmacology In vitro study

Characterized the tannin-rich aqueous extract of bistort rhizome (28 phenolics identified) and demonstrated antibacterial and anti-inflammatory activity, providing a phytochemical rationale for its traditional use as a topical anti-inflammatory and antidiarrheal agent.

Anti-inflammatory Activity of Polygonum bistorta, Guaiacum officinale and Hamamelis virginiana in Rats

Duwiejua M, Zeitlin IJ, Waterman PG, Gray AI (1994) Journal of Pharmacy and Pharmacology Animal study

In a rat model of inflammation, Polygonum bistorta extract showed significant anti-inflammatory activity, supporting the traditional use of the tannin-rich rhizome for inflammatory and swelling conditions.

Historical Texts

Tujing Bencao (Illustrated Classic of Materia Medica), Su Song

Song dynasty, 1061 CE
Records Quan Shen (bistort) among the heat-clearing, toxicity-resolving medicinals, noting the twisted rhizome used for sores and swellings.

Bencao Gangmu (Compendium of Materia Medica), Li Shizhen

Ming dynasty, 1578
Notes the use of the curled rhizome (Quan Shen) to clear heat, resolve toxin and treat sores, abscesses, snakebite and bleeding.

References

  1. Pawłowska KA, Hałasa R, Dudek MK, Majdan M, Jankowska K, Granica S. Antibacterial and anti-inflammatory activity of bistort (Bistorta officinalis) aqueous extract and its major components . Journal of Ethnopharmacology (2020) [DOI]
  2. Duwiejua M, Zeitlin IJ, Waterman PG, Gray AI. Anti-inflammatory Activity of Polygonum bistorta, Guaiacum officinale and Hamamelis virginiana in Rats . Journal of Pharmacy and Pharmacology (1994) [DOI]

This information is for educational purposes only and is not intended to replace professional medical advice. Always consult a qualified healthcare provider before using any herbal remedy, especially if you are pregnant, nursing, or taking medications.

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