Da Huang Zhe Chong Wan

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大黄蟅虫丸 (Rhubarb and Eupolyphaga Pill)

Source: Jin Gui Yao Lue — Zhang Zhong-Jing (Eastern Han, c. 220)

Last updated October 1, 2026

Not yet clinically reviewed

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Description

Da Huang Zhe Chong Wan (Rhubarb and Eupolyphaga Pill), from the Jin Gui Yao Lue (Essentials from the Golden Cabinet) by Zhang Zhong-Jing.

Actions: Breaks up and dispels blood stasis; Generates new blood.

Presentation: Extreme deficiency: emaciation, abdominal distention with an inability to eat, dry, rough and scaly skin, and dark appearance of the eyes with no spirit. These injuries result from the five consumptive lifestyles.

Cautions:

  • Mild self-limiting diarrhea may occur (no need to stop)
  • Bleeding (mostly gums and nose) may occur; stop temporarily if it becomes profuse or prolonged
  • Contraindicated in pregnancy and in amenorrhea due to blood deficiency

Source: Chen JK, Chen TT. Chinese Herbal Formulas and Applications: Pharmacological Effects & Clinical Research. Art of Medicine Press, 2009, p. 937.

Composition

Herb Amount % Role Function
Da Huang
zheng (steamed); as printed: Da Huang (Radix et Rhizoma Rhei) 300g
300g 24.39% Jun (Chief) drains blood stasis, cools blood, clears heat
Tu Bie Chong
as printed: Tu Bie Chong (Eupolyphaga seu Steleophaga) 0.5 cup [30g]
30g 2.44% Jun (Chief) drains blood stasis, cools blood, clears heat
Tao Ren
as printed: Tao Ren (Semen Persicae) 1 cup [60g]
60g 4.88% Chen (Deputy) assists chiefs to activate blood; with Ku Xing Ren moistens dryness and redirects qi
Gan Qi
as printed: Gan Qi (Resina Toxicodendri) 30g
30g 2.44% Chen (Deputy) assists chiefs to activate blood and eliminate stasis in channels and collaterals
Qi Cao
as printed: Qi Cao (Holotrichia) 1 cup [60g]
60g 4.88% Chen (Deputy) assists chiefs to activate blood and eliminate stasis
Shui Zhi
as printed: Shui Zhi (Hirudo) 100 pieces [60g]
60g 4.88% Chen (Deputy) assists chiefs to activate blood and eliminate stasis
Meng Chong
as printed: Meng Chong (Tabanus) 1 cup [60g]
60g 4.88% Chen (Deputy) assists chiefs to activate blood and eliminate stasis
Huang Qin
as printed: Huang Qin (Radix Scutellariae) 60g
60g 4.88% Zuo (Assistant) with Da Huang clears heat from stagnation
Xing Ren
as printed: Ku Xing Ren (Semen Armeniacae Amarum) 1 cup [60g]
60g 4.88% Zuo (Assistant) with Tao Ren moistens dryness, removes stasis, redirects qi
Sheng Di Huang
as printed: Di Huang (Radix Rehmanniae) 300g
300g 24.39% Zuo (Assistant) tonifies blood and nourishes yin
Gan Cao
as printed: Gan Cao (Radix et Rhizoma Glycyrrhizae) 90g
90g 7.32% Shi (Envoy) harmonizes and protects against the harsh herbs
Bai Shao
as printed: Bai Shao (Radix Paeoniae Alba) 120g
120g 9.76% tonifies blood and nourishes yin

Dui Yao — Core Herb Pairs

The classical two-herb combinations at the heart of this formula, as recorded on the herbs' own pages — each pair has an action neither herb has alone.

Da Huang大黄 + Tu Bie Chong土鳖虫

Together they purge and break up long-standing blood stasis, dissolving dry blood and masses.

Consumptive disorder with dry blood: emaciation, abdominal fullness, rough scaly skin, dark eyes. Contraindicated in pregnancy.

Energetics dose-weighted

The formula's overall nature, taste balance and channel reach, weighted by each herb's dose. Classical formulas often pair warm and cool herbs on purpose, so a net figure summarises the mix — it doesn't describe every herb in it.

Nature

Cold Cool Neutral Warm Hot

Net cool (-1.15)

From 100% of the weighed grams.

cold cool neutral warm

Grams by band: cold 56%, cool 15%, neutral 17%, warm 12%.

Small but decisive: Tu Bie Chong 30g (cold, 2% of the grams), Huang Qin 60g (cold, 5% of the grams). Dose weighting nearly cancels a herb this small, but it may be what the formula is for.

Taste

pungent sweet sour bitter salty
  • pungent 1%
  • sweet 22%
  • sour 5%
  • bitter 62%
  • salty 10%

From 100% of the weighed grams.

Channels reached

  • Liver 83%
  • Spleen 49%
  • Heart 42%
  • Large intestine 39%
  • Stomach 37%
  • Kidney 24%

Share of the grams entering each channel, from 100% of the weighed grams.

Dose-weighted from each herb's recorded nature, taste and channels (missing values are left out, never counted as neutral). It describes the composition — it is not a recommendation.

Compare side by side with Liu Shen San →

Preparation

Source text: fine powder formed into honey pills the size of small beans; 5 pills with grain-based liquor three times daily. Today usually 3g pills per dose with warm water.

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Formula family

Contains Di Dang Wan + Xia Yu Xue Tang + Shao Yao Gan Cao Tang + Gan Qi, Qi Cao, Huang Qin and 2 more Di Dang Tang + Di Dang Wan + Xia Yu Xue Tang + Shao Yao Gan Cao Tang + Gan Qi, Qi Cao, Huang Qin and 2 more Xia Yu Xue Tang + Di Dang Wan + Shao Yao Gan Cao Tang + Gan Qi, Qi Cao, Huang Qin and 2 more Shao Yao Gan Cao Tang + Di Dang Wan + Xia Yu Xue Tang + Gan Qi, Qi Cao, Huang Qin and 2 more
Full herb lists
  • This formula = Di Dang Wan + Xia Yu Xue Tang + Shao Yao Gan Cao Tang + Gan Qi, Qi Cao, Huang Qin, Sheng Di Huang and Xing Ren
  • This formula = Di Dang Tang + Di Dang Wan + Xia Yu Xue Tang + Shao Yao Gan Cao Tang + Gan Qi, Qi Cao, Huang Qin, Sheng Di Huang and Xing Ren
  • This formula = Xia Yu Xue Tang + Di Dang Wan + Shao Yao Gan Cao Tang + Gan Qi, Qi Cao, Huang Qin, Sheng Di Huang and Xing Ren
  • This formula = Shao Yao Gan Cao Tang + Di Dang Wan + Xia Yu Xue Tang + Gan Qi, Qi Cao, Huang Qin, Sheng Di Huang and Xing Ren

Each entry reads as the larger formula written out: “+” adds its other catalogue cores, then the herbs none of them hold. A catalogue formula counts as a core only when at least 80% of its herbs are present, no more than 1 is absent, and the absent herb is not its chief.

Formula Network

Formulas that share herbs with this one — the closer to the centre, the stronger the match. Click a node to explore.

Similar Formulas by composition

Match score combines dosage-weighted composition (cosine, 70%) with shared-herb overlap (Jaccard, 30%).

Traditional formula information is for educational purposes only. Herbal formulas should be prescribed by a qualified practitioner — dosages and combinations are individualized and can interact with medications.

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